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Combined drug intoxication (CDI), or multiple drug intake (MDI), is a cause of death by drug overdose from poly drug use, often implicated in polysubstance dependence.
Deaths by combined drug intoxication are relatively rare (one in several million).[1][medical citation needed] In 2004, there were 3,800 deaths in the US resulting from a fatal medication error involving alcohol, while in 1983 there were fewer than 100 such deaths.[2] It is more of a risk for older patients.[3][medical citation needed]
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